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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8806b51272e68f7ed16ec63a047ac7fb3435575620f11024f9a5bf4a3c4ca444' 
  AND token = 't7LozeDRnQ9Z1uJ1B1aD0oKayT7w/x1aQQxsDZRX+9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}