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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4551bd8a8a42a1e5a99db5d8b10a6c4581f2bd7debd4364b20622e14f7339ed7' 
  AND token = 'FU8rxzLkbtCRBUPtGjPNp5c+9OROl/j6odNkQLkQWuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}