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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b905421d04cbb57d38a616607e1c6f13fc2f54461801ea24d3aa5b984534178' 
  AND token = 'n0YFPSyReraGFCT+FScv/jFFhAm3aA1xBttt8ucCS2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}