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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f5084178f1b57053fc803e4c8d89b82906829bc98be73bd8cc12cd929b43c0b' 
  AND token = '2QsD8ZXnRyXRvmIB2MhZ/A/KOoiYmIBfA4q5MegA3DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}