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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d1fde008a2e32f495467a11c3960f993b46240fe614591b80fff9b36acb96e' 
  AND token = 'ozFvwpbuZaDL+ZAruOGNi182gQabwO8DoOGFi3Ucrjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}