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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '310334e2068279df5b4f46074c0c9fe9a0678eca59d50ff8c9fdd112c64a81f5' 
  AND token = 'AXt/T1kIFtDUEAJJG3xprV9hWD7YZIigRqY0dIMiAgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}