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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fc75b562a39105b6663de6a83d1af25c9b56259c5b1aa6438f77d4fc8f3235e' 
  AND token = 'rpzoS4Zb5SDiqDigfGD9oXzXPBsrSSFkjt2BoSIUYvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}