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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21d71f72ee82208cff4818b17a7a42a4b3c4e7a7dce24596208ca7684f70e080' 
  AND token = '5KVIjoxFEuI2BBmx3LNCPQ0UINYf2rI7xK3T37kL3bI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}