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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73886e6893c7646f83337a009869d228e2bf0d7b51deb1a1a2e3d1fbbd7bb330' 
  AND token = '/p7EN+Lm+/uMmDXejVEMMWhEvFDOmO83UqR2YWgHO8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}