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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18bbbc614b19aa9dfff2ff8182faec9c55c2725087041a4e130c7f28bdb778b4' 
  AND token = 'XlCQz+ngeLa6SXSzRColuPkAN7I2afwyKtySx4vsry4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}