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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b44193193125b274fc5473f0171f1b6d4998ecbc8e36087ae705d308fa8f4fbf' 
  AND token = 'IG4B4D4ZmfQ5UpPB4tDrEz9+nNUQPZg6xRGO5uSgPQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}