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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3991a9217ce23d6d7e0ed5cdf497cfe2637c5a314efc5de56da894355a5efdaf' 
  AND token = 'UYEcEA5wdg1bmEotG1N5SxuXaQn94t7vnzpYnyT5mvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}