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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82ab158474be6194d86002dec69fbdac8628368fb86b8128c14ed7328c2f10f8' 
  AND token = 'q3h7nTEiApChVb2Yteuu4Gd3TlR2WWPmtv/fSkNTeHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}