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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35c352513a0b76cf7f816afe8ad0c62ca2b1636cbecd6850bedc5746f8b2f629' 
  AND token = 'VSN8+AEnS8xAUKJ9c4cierhn55b8HCsUsYhe5vPjbeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}