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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e648f261dd5174e1af700d9166360f46d3da2015e13a7ed7d0d5351886fbf35' 
  AND token = 'FfmBj2Q03TwqzWNMLOR70POai6wCKg+jlOzCy/a3ICk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}