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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f0b3dd3cb34102c333c9640ec5b7b5d61fb17db3571234e97e8784c6039b6b' 
  AND token = 'nYBc6lMyQXHlgI5s9GQfR+WVbeSTzjtKw3HfjYRrGjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}