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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc6e1ac04d4495791dedc655b4627ca35e5075985a70c3d32306777f822b824e' 
  AND token = 'dsDUwHj06K9jR7qK5uLlY9jMA6LDUr5MQVSXzlKru5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}