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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e31a2d1099a5fca1aad891a36269e99941f718cb10baebb7e3ea2c33d027b3' 
  AND token = 'bB62t/U38uw6IELUMULRrHo43wzylLDCc3N+wxlB+GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}