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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb8917fef26cde0b5fb4809687af7d668201ca9b5c9f621fe3841bbfe3176c0a' 
  AND token = 'e18rjx2PZSu3thFMIA0IYxtvCZDlk9YEu2i2FzvRbJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}