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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc00a67841960ebf9877e9095e866a7b74d4698ee1155b5561ece11a51b7dd4d' 
  AND token = 'VMcvI7IjcyhzHKFl6t3aHTS+esnBGfDvWGG7FxDsAmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}