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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cf99362f6318b9b6951944d43aadbf4afb4bf983520c2c88074f2488761474a' 
  AND token = 'o6kuot5aQncOOjGaUVrf/vL0A6IiKHA6E1936AFyk+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}