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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2f2507cd5891e05d41df0c95c96b7f7b82bf97765b07777a8f2d94bba0ba341' 
  AND token = 'EPA3vnfVoAVu58N3y0t/0X1C2c4OAs/aXyYp3NCwUhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}