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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec9081eb339f99f4f992b10a8896420b36422f53b0388c4d1885d12669c5a333' 
  AND token = 'wRMweD6sXdSAVMBrTjtrK//9LszgHo9Z/SaxyZeteZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}