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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '896fbb5dc682f8b5b576c520a81202a0a621c1fefa00ec0855f245bed7b3a049' 
  AND token = 'r4vrnXJTx7T/uEpTaK1cfpMoR+E935Ex0gKvwvxxHVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}