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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb20edb928fd5908e0964817e28ee44681efc03a201680fc5ddee20e13f9673f' 
  AND token = 'eJ03anvMXU36lv8Nblp8Kos5f889/MghSCqV4dbZ9+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}