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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644f3eb669de79df1256f4743cebc3d3bab8589fbe041046af94b8823380e3c0' 
  AND token = 'dPPL32nVFbiAR7Rn2yjXbs8cNlYqr1gmWFfMm4FNwX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}