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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aef21a0ed4b13c1e604e47871173f4f6587b73449df85b7352b1346ca2f5c74a' 
  AND token = 'nlsNgeSkHOvzm0HMvwBzwOvq1VGWI+FD0MOby6ggWvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}