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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2533191e4bea5b8fd45f04558d03c178a9948aea3451e226c80251466f4ecfd' 
  AND token = '33n1l0Ac01Qe64phQoM9zwE4R3hMqBTsvuZaCz1H0U4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}