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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2786cd1b5204bfeedc8b7eeb44ba22b20ae52769efd4c017c959875fc53df24f' 
  AND token = '+/hAqUTXscMeD+0jlLn+qZu1YuPkDiYDurdoYyv++4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}