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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2643c447bb4e15787ca7067191169a829a286fbe6c991c0b2eb02f1bd094cbd3' 
  AND token = 'ccNPWmfpnbyt22edZtk6L1OXnbi7XBNtRUfa3ImBmWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}