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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5217512c0406b06e8faec783d7ed68b7adb5a6ffb6dd6311d974bc0f1f8a6847' 
  AND token = 'UvnIOCb/J729qQXzeu+c/9a9AZV6QTXjHUt7jbU7Rw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}