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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f29d9e47ee94ea70330a32442bd0374a60dbbc18a8191194003c3aed7740dfb0' 
  AND token = 'p9IQK2yJD2L2lVmAQiW/VMRve0Wh1R1IKGfZIaWmPQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}