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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '722b2d234d434bb1c6d369b5d1631ce163e49f5202f11ebf9fc25f79db302d88' 
  AND token = '7W4MuLY+1sOlVwOf3XXvP7EuiCtbpoIq1YxH/9noiK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}