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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04d6833b72cbd09f5e663f7f28eb67371d2e2dc7e584b6b44640d6658f6f6b86' 
  AND token = 'tUJsmEUBIs9x1srWxerw5/bpY5v0LvkgnguUh2MxQWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}