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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '043668687a6ea08e0bf75fd6e31968946efacdddf8e4d6dc2fb8b3215823c615' 
  AND token = '9mDDSXZu6YZyIta6SOQx28uhMFzbX/dART5p5wNJeog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}