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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280c55de6e374b11adf6e45f05be6b41e76d3c1eb99effaae247dd342b869dc0' 
  AND token = 'AYfj5JQN2jK9P/F54NPqo02UndVRiyAFPo1DhUipl58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}