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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d318137be21094fb5f15759d66232f294a846f8915da5f39dddc421b6f0e1d7' 
  AND token = 'pcRAJGE2ezdy+CTrr/wgZ1d1nqCPYIq0XKk86yzk1QA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}