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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e285e34ac70c67a6ad3aed780589231a5e6977ab8fac00e2a7025c270e5460a' 
  AND token = 'SbfcCG0FWU238vmY9TvwKn91FMzMU4vhOM8tm7UQ4aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}