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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad8f099874e99d05579507f7d26d7555ed410d956472c4d8883e4c946f80e739' 
  AND token = 'IU5OQPNCvr098gMZ9aeYLe4Bttr+lsppvC+hc/qyc5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}