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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8115aaf478489a252e2d876acfbce0fc7dbb012326b53f29d9536b98b7221409' 
  AND token = 'K7be/BaR6UuK8AvN+w0orW7sfV8ZtZaXixmlZrm7UEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}