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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1fdc55ce7cd46f7ec596d05b01876dcdc2982c6d962282726782fd8162ec20e' 
  AND token = 'PUoq46WlEzwE/2baRBnywv4gb9wRCoTr3inIHskMIqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}