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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '171b5b313ef06363c166b6bf6e0f9e187c641f0d9433eed790ada6b12ced5d33' 
  AND token = 'YFlVXee60XXMNwf6gy8xjOXcekKiSW1Ge2hcEwJWSxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}