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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5d1d2d0502aae34debcd30602eaa24a1583a3d2af6e34146655fa2dd3138e38' 
  AND token = 'aKKPFoRO1VlWCl2xAycmxNifFt9Sh+hRIgOQsIrN6Og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}