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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84f2e9b739540c79e9c875a95985721c57339f3053005747fb9f58b7dad0da94' 
  AND token = 'pVa4JjNgERzHN+PBPNnsyA4Vc1BSIQMXa60yZ2iic0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}