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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc107d4d65bd9f795d19f5543e066f717a6a0836e5f898c6b3a6a361203affb6' 
  AND token = 'i4+bCZn5z1xHpQxho3T4//09+WXZeD5ScLQ+oMZdwuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}