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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3650ae2972a79fdb1a5842b5676a2db4f31ff4bbfac81de1ffd5703545d2c45' 
  AND token = 'YDNrb2d85JHMm1rYoVmpmWTyv9Sap+2QoOsZDMvUXpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}