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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4727c7649f82719f462d48c5da32ec01f9c9dd39041bf7ca27010b7ee8c0b3ec' 
  AND token = '72tSmyG9BHMAWt8kYXY5l+1dUUYMBD0+azr9EMDF3nM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}