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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f27a24b0c0114276f44310f4a5913cc6c02fe522b940df09e0f4eb4f1beeeac' 
  AND token = '38UDaR9LbNiQnYY8UIT8eY2JMsUT0AvDMm8M+AZAnak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}