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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b4d288c8e3cd8b2417e3055be850f53db4ec37bb016f248598ec9ea8e9f82b' 
  AND token = 'YeFWLzXj8ehmV5q8Rg85/XGoNnEIoMY54rJKXs6IaiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}