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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fbe01754d10e2612f0ce9b5901427661fc26972a38f0285db0e0f41acc0cd4e' 
  AND token = '3PL43oPkL5kLF46xfvBtoRJkKSa6MzUtbCF1dFC0Xkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}